Induced pluripotent stem cell-derived (iPSC) organoids offer unprecedented opportunities to study human development, disease, and drug responses in a controlled in vitro environment.
These 3D models mimic the functionality of human organs and new methodologies are being rapidly developed to study their complex physiological structure and processes.
Gain deep insights into 3D human in vitro organoid models with label-free, live-cell assays from Axion BioSystems.
Advantages iPSC organoid models
Organoids are a powerful tool for biological research.
Advantages of iPSC organoids:
- Functional similarity
iPSC organoids recapitulate complex physiological processes seen in vivo. - Self organizing
iPSC organoids self-organize into 3D structures similar to tissues in vivo. - Cellular diversity
iPSC organoids are often comprised of multiple cell types found in their target organ (e.g. neurons & glial cells).
With increased physiological relevance organoids are used for applications in drug screening, disease modeling, and personalized medicine.
Assays for iPSC organoid characterization and function
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Standardizing neural organoid production and analysis>
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Neural organoids model development and maturation of brain networks>
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Cardiac organoids to model ischemia-reperfusion injury>
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Label-free tracking of hepatic organoids in vitro>
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Publication Highlight: Live-cell imaging with 3D models>
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Additional Resources: Neural Organoids>
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Publications: Cardiac Organoids>
Quality neural organoid research requires the right tools from start to finish.
Watch this 8 minute video to discover how Axion's imaging and MEA platforms allow you to capture the complex biology of organoids non-invasively and in real time.
