Maestro Z

Axion BioSystems Maestro Z

Maestro Z

Track cell proliferation, viability, morphology, and immune cell-mediated killing with the Maestro Z™.

Axion BioSystems Maestro Z platform offers impedance-based cell analysis for real time, continuous, label free monitoring of your cells. Continuous data reveals the kinetics of cell-cell interactions and cell-drug responses for better mechanistic understanding without the time- and cost-intensive process of repeating multiple endpoint assays.

Now with a smartphone app allowing you to check on your experiment from outside the lab.

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Key Features

 

Real-time, live-cell analysis platform

 

Taking care of the assay so you can focus on the science.

>> Monitor your experiments from outside the lab
The new Maestro Z App allows you to check in on your cells and experiment to ensure everything is running smoothly while you are away from the lab.

 

>> Precisely control the cells
There is no need for an additional cell culture incubator, saving valuable lab space and money. Maestro Z’s smart environmental chamber finely controls temperature and CO₂ while rejecting electrical noise and mechanical vibrations.

>> Continuous cell monitoring
96 simultaneous live recordings from your cells. The Maestro Z system performs noninvasive electrical measurements from the cultured cell population, circumventing the use of dyes/reporters that can perturb your cell model and confound results. Track activity over hours and weeks from the same population of cells label free and in real time.

>> See your cells
Maestro Z’s transparent CytoView-Z™ 96-well plates have a viewing window in each well, allowing for cell visualization and assay multiplexing.

>> Start your assay with the push of a button
“One button setup,” means temperature and CO₂ levels automatically adjust on plate docking. Plate usage is logged via an integrated plate barcode scanner for convenient experiment tracking.

>> Review your results faster
The Impedance module with AxIS Z™ software provides a simplified approach to the setup, execution, and analysis of experiments.

Multiple Maestro Z support available

>> Increase throughput with multiple Maestros
Continuously monitor multiple plates automatically and simultaneously with multiple Maestro support. Save space in your lab by controlling multiple Maestro systems using a single computer.

 

 

Axis Navigator software links to imaging data in the Axion Portal

Multiplex your assay: Maestro + Omni

>> Platform cross-compatibility lets you view live-cell imaging alongside real-time, functional data to enhance your analysis

>> Monitor electrode coverage and cell morphology to ensure consistent, quality results

>> Experience no-hassle tracking—the Axion Portal automatically links data via barcode

Learn more

 

Overview

 

Maestro Z overview

 

 

Cell-based assays enable rapid evaluation of human biology in vitro, with substantial advantages in throughput and cost over tissue or animal models. However, many cell-based assays are endpoint assays, limited to a single snapshot in time. Axion BioSystems’ Maestro Z platform offers impedance-based cell analysis for real time, continuous, label free monitoring of your cells. Continuous data reveals the kinetics of cell-cell interactions and cell-drug responses for better mechanistic understanding without the time- and cost-intensive process of repeating multiple endpoint assays.

Maestro Z Product Family

 

Impedance software modules for Maestro Z

Software

The Maestro Z system is available with two software modules: Impedance and GxP Impedance. Select the software modules to match your assay needs:

Impedance – Track cell proliferation, morphology, and viability label-free and in real-time. Ideal for immuno-oncology, cytotoxicity, virology, cell migration, cell proliferation, GPCR assays, and many more.

GxP Impedance – Achieve FDA 21 CFR Part 11 compliance in GMP/GLP labs with this version of the Impedance Software Module.

Cells growing to confluence over microelectrode array

Consumables

The Maestro Z system is compatible with the 96-well impedance assay plate.

CytoView-Z™ – The Maestro impedance plate with a transparent well bottom for cell visualization and assay multiplexing. Available in a 96-well plate format.

Omni live-cell imaging platform

Cross-compatible Platforms

The Maestro Z system has cross-compatibility with:

Omni™ – Complement your impedance assays with whole-plate images of your cultures. View electrode coverage and culture health over time with just a few clicks in AxIS Z. Compatible with the Omni and Omni Pro 12™ systems.

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