Discover next-generation live-cell analysis
The Maestro Z platform is the simple, sensitive, in vitro solution for real-time cell analysis. Requiring no labels or dyes, it measures complex cellular kinetics without disturbing the underlying biology. With powerful, interactive software for fast results, see how you can accelerate your research with Maestro Z.
![Label-free data](/sites/default/files/inline-images/Label%20free%20data.png)
Continuous label-free data
![Measurements](/sites/default/files/inline-images/Measurable.png)
Sensitive measurement
![User Friendly Live Cell Analysis Software](/sites/default/files/inline-images/Friendly%20Software.png)
Friendly analysis software
The complete assay platform
Featuring sensitive cellular impedance electrodes, precise environmental controls, and integrated automation features, the Maestro Z impedance platform has everything you need to generate reliable, reproducible data.
Key features
>> Simultaneous full-plate recording
>> Built-in environmental controls
>> Powerful, intuitive software
>> Automation compatibility
>> Transparent plates
>> Barcode plate tracking
>> 21 CRF Part 11 compliant
![Maestro ZHT from Axion BioSystems](/sites/default/files/inline-images/Maestro%20ZHT%20%282%29.png)
See what endpoint assays miss
Maestro Z captures all stages of your experiment in one plate. Reveal dynamic, kinetic responses with the power of cellular impedance and see what your endpoint assays aren’t telling you.
>> Don’t disturb the underlying biology
>> Capture chronic and acute responses
>> See the full time course and analyze kinetics
![Maestro Z Endpoint assays](/sites/default/files/inline-images/Maestro%20Z%20endpoint%20assays.jpg)
One instrument, many uses
Cellular impedance is a proven and well-established technique for monitoring key parameters of cell structure and behavior, making Maestro Z a versatile platform adaptable to the many assay needs of your lab. The Maestro Z platform can measure:
No labels, dyes, or complicated steps
There’s no optimization of labels, dyes, or incubation times. No lot-to-lot reagent variability to confound your results. Replace costly endpoint assays with Maestro Z or easily multiplex with your favorite assays to supplement your research. Running the assay couldn’t be easier:
![Maestro Z Workflow](/sites/default/files/inline-images/Maestro%20Z%20Workflow.jpg)
1. Plate & culture your cells normally
2. Record on the Maestro Z and dose
3. Analyze your data
Accelerate your research with better, faster data
![Kinetics](/sites/default/files/inline-images/Kinetic%20Data%20%282%29.png)
Compare conditions and make decisions on comprehensive datasets with just one plate. Here, different gene editing methods demonstrated different kinetics, only revealed by a continuous live-cell assay.
![Kinetic Data](/sites/default/files/inline-images/Kinetic%20Data.png)
![Software Sensitivity](/sites/default/files/inline-images/Software%20Sensitivity.png)
Sensitive electrodes provide a high degree of resolution. The Maestro Z assay was able to differentiate E:T ratios in this cell killing assay to effectively compare therapeutic potencies.
![Cell Killing Assay](/sites/default/files/inline-images/Cell%20Killing%20Assay.png)
![Reliable and reproducible data](/sites/default/files/inline-images/Label%20free%20data_0.png)
The simplicity of the assay ensures reliable, reproducible data. Here, minimal intra-assay variability is observed between plates.
![Reproducibility](/sites/default/files/inline-images/Reproducibility.png)
The ideal tool for discovery
Whether characterizing the development of disease models or screening new therapeutics, quality functional readouts are essential for making informed decisions. The Maestro Z platform is an essential tool in academic and pharmaceutical labs worldwide.
>> Virology
Track cytopathic effects for real time viral titer, antiviral, and neutralization assays.
>> Barrier function
Monitor cellular barrier integrity using transepithelial electrical resistance (TEER).
Focus on the science rather than the software
Simplify the setup, execution, and analysis of your experiments and go from raw data to final figures faster with AxIS Z. Included with all Maestro Z instruments, AxIS Z makes keeping track of your experiments simple:
>> No setup required to begin recording
>> Automated barcode and event tracking ensures data integrity and effortless multiuser compatibility
>> Integrated experiment database lets you search for files by name or metadata
>> Mobile app to monitor your experiment outside the lab
>> Multilayer platemapping lets you track all conditions
Continuous data, instant analysis
Go from raw data to results in just a few clicks. AxIS Z’s user-friendly design ensures fast, reliable data analysis.
>> Get multiparameter analysis of kinetic and endpoint value
>> Toggle between (1) raw values, (2) calculated, or (3) EC50 at with a click
>> View live, fully interactive plots with quick two-click export options
>> Automatically apply control wells and normalizations/ corrections
![User friendly design with Live Cell Analysis Software](/sites/default/files/inline-images/software%20analysis.jpg)
Fully editable figures all in one place
Don’t get bogged down with analysis file bloat. AxIS Z’s Lab Notebook lets you collect every plot of interest during analysis and export it all to a single Excel file that tracks the original source and settings for each one.
Fully customizable plots and data tables summarizing your experiment are instantly ready to copy into presentations or your preferred plotting software.
![AxIS Z Lab Notebook Feature](/sites/default/files/inline-images/lab%20notebook.jpg)
Choose the
Maestro Z for you
Maestro ZHT: The best benchtop live-cell assay system
Continuous, real-time 384-well measurements in a compact footprint will make the Maestro ZHT the most productive spot on your bench. Featuring integrated environmental controls and automation compatibility, meet your lab’s new workhorse.
Maestro TrayZ: An assay powerhouse in your incubator
With a thin multiplate design developed to accommodate multiple trays in one incubator, Maestro TrayZ is perfect for labs with limited bench space or multiple users and simultaneous experiments.
Maestro Z: Quality data at an affordable price
The Maestro Z makes quality real-time data accessible to any lab. The introductory system boasts a small benchtop footprint with fully integrated environmental controls.
Impedance systems features comparison
There’s a Maestro Z solution for every lab. Choose the device that works best for you.
![Maestro Z Platform Comparison Table](/sites/default/files/inline-images/Maestro%20Z%20Platform%20Comparison_1.jpg)
Our commitment to our customers
With over 15 years of experience bringing innovative new products to our customers, we strive to accelerate your research by making live, functional biology more accessible. Our design philosophy is to ensure all of our products are:
![Flexible](/sites/default/files/inline-images/Flexibility%20Icon.png)
Flexible
Hardware designed for broad, integrated functionality in one instrument
![Easy to use](/sites/default/files/inline-images/Easy%20to%20Use%20Icon.png)
Easy to use
Intuitive instruments, consumables, and software for fast, easy adoption
![Smart Tech](/sites/default/files/inline-images/Smart%20Tech%20Icon.png)
Smart technology
Easy to run with no complicated steps, saves time and money.