Maestro Z Platform Brochure

 

Discover next-generation live-cell analysis

The Maestro Z platform is the simple, sensitive, in vitro solution for real-time cell analysis. Requiring no labels or dyes, it measures complex cellular kinetics without disturbing the underlying biology. With powerful, interactive software for fast results, see how you can accelerate your research with Maestro Z.

Label-free data
Continuous label-free data
Measurements
Sensitive measurement
User Friendly Live Cell Analysis Software
Friendly analysis software

 

The complete assay platform

Featuring sensitive cellular impedance electrodes, precise environmental controls, and integrated automation features, the Maestro Z impedance platform has everything you need to generate reliable, reproducible data. 

Key features

>> Simultaneous full-plate recording

>> Built-in environmental controls

>> Powerful, intuitive software

>> Automation compatibility

>> Transparent plates

>> Barcode plate tracking

>> 21 CRF Part 11 compliant

Maestro ZHT from Axion BioSystems

 

See what endpoint assays miss

Maestro Z captures all stages of your experiment in one plate. Reveal dynamic, kinetic responses with the power of cellular impedance and see what your endpoint assays aren’t telling you.

>> Don’t disturb the underlying biology

>> Capture chronic and acute responses

>> See the full time course and analyze kinetics

Maestro Z Endpoint assays

 

One instrument, many uses

Cellular impedance is a proven and well-established technique for monitoring key parameters of cell structure and behavior, making Maestro Z a versatile platform adaptable to the many assay needs of your lab. The Maestro Z platform can measure:

Cell Proliferation Assay
Proliferation
Cytotoxicity Application
Cytotoxicity
Barrier Function/TEER Application
Barrier/TEER
Cell Signaling Application
Signaling
Morphology Application
Morphology

 

No labels, dyes, or complicated steps

There’s no optimization of labels, dyes, or incubation times. No lot-to-lot reagent variability to confound your results. Replace costly endpoint assays with Maestro Z or easily multiplex with your favorite assays to supplement your research. Running the assay couldn’t be easier:

Maestro Z Workflow

 

1. Plate & culture your cells normally

2. Record on the Maestro Z and dose

3. Analyze your data

 

Accelerate your research with better, faster data

Kinetics

Compare conditions and make decisions on comprehensive datasets with just one plate. Here, different gene editing methods demonstrated different kinetics, only revealed by a continuous live-cell assay.

Kinetic Data


 

Software Sensitivity

Sensitive electrodes provide a high degree of resolution. The Maestro Z assay was able to differentiate E:T ratios in this cell killing assay to effectively compare therapeutic potencies.

Cell Killing Assay


 

Reliable and reproducible data

The simplicity of the assay ensures reliable, reproducible data. Here, minimal intra-assay variability is observed between plates.

Reproducibility


 

 

The ideal tool for discovery

Whether characterizing the development of disease models or screening new therapeutics, quality functional readouts are essential for making informed decisions. The Maestro Z platform is an essential tool in academic and pharmaceutical labs worldwide.

Oncology Application Data
>> Oncology

Evaluate cancer cell invasion, proliferation, and killing in real time.

Virology Application Data
>> Virology

Track cytopathic effects for real time viral titer, antiviral, and neutralization assays.

Barrier Function Application Data
>> Barrier function

Monitor cellular barrier integrity using transepithelial electrical resistance (TEER).

 

Focus on the science rather than the software

Simplify the setup, execution, and analysis of your experiments and go from raw data to final figures faster with AxIS Z. Included with all Maestro Z instruments, AxIS Z makes keeping track of your experiments simple:

>> No setup required to begin recording

>> Automated barcode and event tracking ensures data integrity and effortless multiuser compatibility

>> Integrated experiment database lets you search for files by name or metadata

>> Mobile app to monitor your experiment outside the lab

>> Multilayer platemapping lets you track all conditions

Live Cell Analysis Impedance Software for Maestro Z Platform

 

Continuous data, instant analysis

Go from raw data to results in just a few clicks. AxIS Z’s user-friendly design ensures fast, reliable data analysis.

>> Get multiparameter analysis of kinetic and endpoint value

>> Toggle between (1) raw values, (2) calculated, or (3) EC50 at with a click

>> View live, fully interactive plots with quick two-click export options

>> Automatically apply control wells and normalizations/ corrections

User friendly design with Live Cell Analysis Software

 

Fully editable figures all in one place

Don’t get bogged down with analysis file bloat. AxIS Z’s Lab Notebook lets you collect every plot of interest during analysis and export it all to a single Excel file that tracks the original source and settings for each one.

Fully customizable plots and data tables summarizing your experiment are instantly ready to copy into presentations or your preferred plotting software.

AxIS Z Lab Notebook Feature

 

Choose the

Maestro Z for you

Maestro ZHT: The best benchtop live-cell assay system

Continuous, real-time 384-well measurements in a compact footprint will make the Maestro ZHT the most productive spot on your bench. Featuring integrated environmental controls and automation compatibility, meet your lab’s new workhorse.  

Maestro ZHT
Maestro TrayZ: An assay powerhouse in your incubator

With a thin multiplate design developed to accommodate multiple trays in one incubator, Maestro TrayZ is perfect for labs with limited bench space or multiple users and simultaneous experiments.

Maestro TrayZ
Maestro Z: Quality data at an affordable price

The Maestro Z makes quality real-time data accessible to any lab. The introductory system boasts a small benchtop footprint with fully integrated environmental controls.

Maestro Z

 

Impedance systems features comparison

There’s a Maestro Z solution for every lab. Choose the device that works best for you.

Maestro Z Platform Comparison Table

 

Our commitment to our customers

With over 15 years of experience bringing innovative new products to our customers, we strive to accelerate your research by making live, functional biology more accessible. Our design philosophy is to ensure all of our products are:

Flexible

 

Flexible

Hardware designed for broad, integrated functionality in one instrument

 

Easy to use

 

Easy to use

Intuitive instruments, consumables, and software for fast, easy adoption

 

Smart Tech

 

Smart technology

Easy to run with no complicated steps, saves time and money.